SEK-1 IS IMPORTANT IN TISSUE-SPECIFIC REGULATION OF INNATE IMMUNITY DURING THE XOO INFECTION IN THE MODEL HOST CAENORHABDITIS ELEGANS

sek-1 is important in tissue-specific regulation of innate immunity during the Xoo infection in the model host Caenorhabditis elegans

Xanthomonas oryzae RCA pv.Oryzae (Xoo) are plant pathogenic bacteria that can cause serious blight of rice.We have demonstrated that Xoo can infect the model organism C.elegans and p38 MAPK pathway plays specific roles in defense against the pathogen in our previous paper.Based on that p38 MAPK pathway can be activated in a range of tissues, it is

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A new extended Chen distribution for modelling COVID-19 data.

In this paper, we propose a new flexible statistical distribution, the Topp-Leone Exponentiated Chen distribution, to model real-world data effectively, with a particular focus on COVID-19 data.The motivation behind this RCA study is the need for a more flexible distribution that can capture various hazard rate shapes (e.g., increasing, decreasing,

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Bright future or blind alley? CAR-T cell therapy for solid tumors

Chimeric antigen receptor (CAR) T cells therapy has emerged as a significant breakthrough in adoptive immunotherapy for hematological malignancies with FDA approval.However, the application of CAR-T cell therapy in solid tumors remains challenging, mostly RCA due to lack of suitable CAR-T target antigens, insufficient trafficking and extravasation

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